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doi: 10.1200/JCO.2010.30.4154
This is an important study because its the first time a weight loss drug has been shown to reduce the risk of heart disease, including the risk of death, says Howard Weintraub, MD, clinical director of the Center for the Prevention of Cardiovascular Disease, part of NYU Langone Heart
What this means for clinical research: Trial design and risk management are becoming more predictive and front-loaded, enabling earlier go/no-go decisions and reducing late-stage surprises across clinical programs
Always consult your GP or a specialist before making any changes to your treatment or seeking participation in research
It inhibits the cysteine/glutamate antiporter system Xc-, thereby revoking cysteine import and thus reducing glutathione synthesis
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