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3c), compounds 1 - 5 were found to be slow inhibitors as they displayed little to no inhibition after 15 min, but time-dependent inhibition of TGR over 25 h (Fig

As an example pathway to decrease conditioned consummatory behavior, VTA GLP-1R signaling potentially controls for palatable food intake by modulating the rewarding value of the ongoing meal while having fewer effects on between-meal satiety processes

GLP-1 medications can help offset some of these changes

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