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Testosterone provides powerful anti-catabolic effects that protect muscle during energy deficits

After labeling, the cells were washed four times with internalization buffer (HBSS supplemented with 20 mM HEPES, 1 mM CaCl 2 , 1 mM MgCl 2 )

That leaves a significant opportunity for new oral formulations to make a major impact, as patient preference leans heavily towards pills over injections

Biochem Biophys Res Commun 357:5758, PMID: 17434454 Li Y, Cohenford MA, Dutta U, Dain JA (2008) The structural modification of DNA nucleosides by nonenzymatic glycation: an in vitro study based on the reactions of glyoxal and methylglyoxal with 2-deoxyguanosine

Preserving muscle is critical because muscle helps: Maintain metabolic rate Support strength and mobility Improve body composition Prevent weight regain The goal is not just to lose weight, but to lose fat while maintaining muscle