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Recently, it has been argued that oral intake of other antioxidants, including vitamin C and E, do not elevate PGC-1 in the skeletal muscle of mice and humans [29,30]
To reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes mellitus who are at high risk of these events
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