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However, ICV administration of higher doses of GLP- 1 (1 and 3 nmol) and GIP (6 nmol) significantly reduced food intake and body weight

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doi: 10.1002/oby.20660

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Further analysis confirmed that FOXO4-positive cells co-expressed Leydig cell markers, specifically StAR and CYP11A1, indicating that FOXO4 is indeed expressed in human Leydig cells [1]

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