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Cell Death Differ 16 , 13031314 (2009)

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Product Information Product Literature & Protocol FAQs & Troubleshooting References Supporting Documents Product Information Advantages & Features: Hypermedin is a biosuperior recombinant human somatomedin C that is more potent than wildtype IGF-I or LR3-IGF1 Hypermedin supplementation supports human pluripotency Aids derivation of new ES cell lines from epiblasts of human blastocysts Hypermedin is manufactured xenogen-free for establishment of chemically-defined media that supports human pluripotent stem cells (hPSCs) IGF1/insulin signaling via AKT/mTOR may obviate exogenous FGF2 supplementation in hPSC media Source: Human IGF1 was improved through protein engineering efforts including directed evolution and rational design

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