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The secretion of GH in both fish and mammals follows a pulsatile, circadian pattern, with relatively higher release during the dark phase ( Main Hormonal Regulators of SomatotrophsGHRH and Somatostatin Two brain (hypothalamus)derived modulating factors, the stimulator GHRH and the inhibitor somatostatin ( Figure 1 ) (77, 78), birds and mammals (78, 79)

Start with the lowest effective dose and monitor for side effects in the first 24 hours

doi: 10.3390/molecules27134315