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The Importance of Metabolism Besides dose, what your body does with a particular substance, how it gets metabolized and the biologic effect those metabolites exert are all critical factors in determining if that substance is truly friend or foe

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10.1007/s001250050903 [DOI] [PubMed] [Google Scholar] 37.Adelhorst K, Hedegaard BB, Knudsen LB, Kirk O

The -glutamatyl cycle or Meister cycle initially proposed in the 60s described the synthesis and breakdown of GSH, making it a strong cysteine donor in physiological and pathological conditions (32)