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2 Overview of osteoarthritis and ferroptosis 2.1 Pathogenic mechanisms of osteoarthritis OA is a common degenerative joint disease marked by gradual cartilage degradation, destruction of subchondral bone structure, synovial inflammation, and clinical symptoms such as joint pain

Non-protein-bound uremic toxins are divided into free water-soluble low molecular weight uremic toxins and middle molecule uremic toxins

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