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In 3xTg-AD mice, dietary SAMe supplementation reduced hippocampal A and phosphorylated tau, and delayed the accumulation of extracellular A, demonstrating SAMes ability to modulate the time course of AD neuropathology (21, 23)

Data availability All data generated or analyzed during this study are included in this published article and its supplementary information files

In contrast, ironsulfur cluster-binding glutaredoxins such as ScGrx3-5 have a modified loop and helix 3 (Fig

143 Salidroside downregulates the levels of NLRP3, ASC, caspase-1, and IL-1 and significantly protects the liver from APAP overdose in C57BL/6 mice

63 Nianiou-ObeidatI.MadesisP.KissoudisC.VoulgariG.ChronopoulouE.TsaftarisA.et al (2017)