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Zepbound overtook Novo Nordisk's current injectable obesity therapy Wegovy (semaglutide) in the fourth quarter of 2025, and Novo Nordisk had banked on CagriSema as a near-term growth driver while other candidates in its weight-loss pipeline proceed through clinical testing

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More research is needed to fully understand how GLP-1 medications affect pregnancy and pregnancy planning, so using reliable contraception while taking this type of medication is suggested (2)

Semaglutide is the active ingredient behind blockbuster therapies such as Ozempic and Wegovy developed by Novo Nordisk