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Clin Pharmacol (2022) 14:617

Metabolite accumulation and measurement were as also done earlier in bacterial cells employing the FRET-based genetically encoded sensors 28,29

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Their findings also showed a reduction in 3 and 17-hydroxysteroid hydrogenase (3-HSD and 17 -HSD) activities, as well as testosterone, luteinizing hormone (LH), and FSH levels